

Prompt: A comprehensive scientific diagram divided into two panels, BioRender style, illustrating NSCLC heterogeneity. Upper Panel (Spatial): A detailed tissue landscape showing mCAF fibroblasts building collagen barriers to exclude T-cells, and vCAFs interacting with Tregs near blood vessels. Lower Panel (Temporal): A timeline visualization showing the evolution of tumor clones and T-cells, depicted as flowing colorful river charts (Muller plots) changing size over time, indicating drug resistance. Connected by arrows showing the link between space and time. Clean white background, professional medical color palette (blue, red, grey), isometric view, 8k resolution. --ar 3:4 --v 6.0
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