

Figure 2: Translational Roadmap for CB2 Therapeutics(Prompt for BioRender / Designer):Concept: A timeline or flow chart from “Current Challenges” to “Future Solutions”.Step 1: The Obstacles. Icons representing:Desensitization: A receptor disappearing into the cell.Genetics: DNA strand with a mutation marker “Q63R”.Barrier: Drug molecules bouncing off thick skin.Step 2: The Solutions (Arrows pointing to).Biased Agonism: A molecule selectively hitting one pathway (G-protein) but not the other (ββ-arrestin).Stratification: Grouping patients by Gene type.Nanotechnology: Draw a Lipid Nanocarrier (sphere) successfully penetrating the skin layers.Goal: To visualize the “Precision Medicine” approach discussed in Section 6.
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