

Flat 2D vector scientific schematic, BioRender-style, minimalistic, conceptual diagram. No 3D, no photorealism, no gradients, no shadows, no textures. Simplified shapes, clean outlines, clear arrows. Minimal labels only.Mechanistic illustration of the gut–brain axis in metabolic disease. Gut microbiome dysbiosis increases production of Imidazole Propionate (ImP) by bacteria such as Eggerthella lenta. ImP crosses the intestinal barrier, enters the bloodstream, and reaches the brain across the blood–brain barrier. In the hypothalamus, ImP alters neuronal gene expression and disrupts GABAergic and glutamatergic signaling, leading to stress-related behaviors and emotional eating. Includes gut, blood vessels, hypothalamus, mouse and human elements. Publication-ready figure.Negative prompt: 3D, realistic anatomy, photorealistic, artistic, cartoon, anime, expressive faces, dramatic lighting, textures, shadows, hand-drawn, sketch, decorative fonts, long text
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