

Scene Composition: Split view showing the outcome (Pathology) vs. Intervention (Rescue). 1. Pathological Consequence (Left side): “Schematic graph showing Excitation/Inhibition (E/I) balance scale tipping heavily towards Excitation. Beside it, an EEG trace showing high-amplitude, hypersynchronous γ γ-band oscillations.” Labels: “Increased E/I Ratio”, “Reduced sIPSC (50% ↓ ↓)”, “Hypersynchrony ( γ γ-band)”, “Chronic Spontaneous Epilepsy”. 2. Intervention/Rescue (Right side): "Three blockage symbols (red ‘X’) on the mechanism arrows: Microglia depletion. Microglial GABA receptor knockout. Astrocyte C3 knockout." “Result visual: Intact inhibitory synapses on the soma. EEG trace showing normal rhythm.” Labels: “Rescue”, “Preserved Inhibitory Synapses”, “Seizure Reduction (60-70%)”.
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