扁平化医学科研示意图CD74mTOR轴脊髓损伤神经

Dual Mechanisms of the CD74/mTOR Axis in Exacerbating Neurological Deficits Post-SCIProfessional Biorender-style mechanism diagram. Clean layout, scientific color coding.Layout (Top to Bottom): Trigger: "Spinal Cord Injury" icon. Below, show microglia activation with "CD74↑" label. Hub: Arrow to central "mTOR Activation" module. Pathways: Left (Red/Orange): Arrow to "Inhibits OXPHOS" (dysfunctional mitochondrion) → "Neurotoxic Microglia" → "Neuronal Death & Myelin Debris". Right (Brown/Gold): Arrow to "Fatty Acid Shift" (lipid droplets) → "Impaired Debris Clearance" (phagocytosis block) → "Hindered Axon & Circuit Regeneration". Outcome: Pathways converge on "Worsened Motor Deficit" icon. Color Code: Injury (Blue-grey), mTOR hub (Accent), Left path (Red/Orange), Right path (Brown/Gold), Outcome (Dark). Clear arrows.