BioRender-style vertical

BioRender-style vertical schematic: "Lactate's Context-Dependent Immune Role".Three panels on white background:Top (TME - Suppressive): High lactate (orange circles). Show uptake into cells via MCT. Results: CD8+ T cell dysfunction (↓cytotoxicity), Treg activation, impaired DC function. Use blue inhibitory arrows.Center (Autoimmunity - Inflammatory): Inflamed tissue, high lactate. Uptake into: T cells (↑IL-17/IFN-γ), M1 macrophages (↑TNF-α), active neutrophils. Use red activating arrows.Bottom (Infection - Suppressive): Pathogens present, lactate high. Promotes: T cell exhaustion (↑PD-1), M2 macrophages (↑IL-10). Use blue inhibitory arrows.Style: Flat vector icons. Color code: Lactate=orange, Suppression=blue, Inflammation=red. Clean layout, minimal text labels.